Seven academicians from the Chinese Academy of Sciences have created a sensational event for the industry

New yan south flying autumn sky, thousands of Lin red leaves fresh color. On October 21, 2023, the 21st Advanced Technology Seminar and Exhibition of Modern Scientific Instruments, sponsored by Modern Scientific Instrument Network and co-organized by Beijing Haigang Instrument Co., Ltd. and the Key Laboratory of Terahertz Optoelectronics of the Ministry of Education, was held in Xiangshan, Beijing. Guangzhou Zero Time Visual Culture Media Co., LTD., as the designated one-stop conference service provider of this seminar, brings you the special report of this conference.

The conference is one of the highest standards in the industry. Academician Yang Guozhen of Institute of Physics, Chinese Academy of Sciences, Academician Wang Erkang of Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Academician Dong Shaojun of Changchun Institute of Applied Chemistry, Academician Zhuang Songlin of Shanghai University of Science and Technology, Academician Yang Xiurong of Changchun Institute of Applied Chemistry, Chinese Academy of Sciences attended the conference. In addition, it also attracted many experts and scholars in the industry to participate in this seminar to discuss the new principles, new methods, new technologies, new instruments and new applications that have emerged in the scientific instrument industry in recent years.

Academician Yang Guozhen, Institute of Physics, Chinese Academy of Sciences, delivered a wonderful speech for the seminar. "Terahertz waves have important research value and application value. Terahertz spectral imaging belongs to the national major scientific and technological needs, and is a scientific research project strongly supported by the state. By studying the propagation characteristics of terahertz waves and the mechanism of interaction with matter, it is helpful to reveal the basic structure and properties of matter, and provide strong support for national scientific and technological innovation and industrial development. I hope that you will make use of this rare opportunity to make a greater impact." Academician Yang expressed such wishes and expectations. Finally, Academician Yang wished the seminar a complete success.

　Professor Liu Chengyan, Vice chairman of the China Association of Analysis and Testing, expressed his heartfelt thanks to all the participants. Professor Liu said that scientific instruments are the equipment basis for human exploration of the unknown world, observation of new things, acquisition of new data and disclosure of new laws, and play a decisive role in the development of the discipline. Many of the current scientific achievements can not be separated from the progress of scientific instruments, the realization of double carbon goals, green development, the construction of digital China and other major projects need scientific instruments to illuminate the road ahead, with the love of the industry, Professor Liu called on the participants to take this meeting as an opportunity to unite forces from all walks of life, to make greater contributions to the cause of scientific instruments.

　　Hu Baishun, chief editor of Modern Scientific Instruments, said that the current rapid development of social science and technology, master the cutting-edge technology of scientific instruments that master the commanding heights of science and technology competition. Nowadays, China's mass spectrometer manufacturers have mushroomed and are in a stage of vigorous development. Terahertz wave technology is known as one of the four technologies that change the future of the world, and is now widely used in agriculture, medical care, national defense, astronomy and other fields. It is hoped that through this conference, participants can strengthen exchanges and cooperation and jointly promote the application and development of terahertz wave technology. The innovation and development of scientific instrument technology benefit mankind and create a better future.

Academician Li Jinghong of Chinese Academy of Sciences/Tsinghua University delivered a VCR speech for the symposium. Academician Li Jinghong said that modern scientific instruments are important tools and means for human knowledge acquisition and exploration of the unknown world, and are the cornerstone and source of scientific and technological innovation, and the science and technology of major countries are closely related to it. In recent years, China's major strategies such as artificial intelligence, new energy, new materials, semiconductor biomedicine, emerging industries, and forward-looking research are inseparable from the equipment and guarantee of scientific instruments. Finally, Academician Li Jinghong hopes that the participants will actively communicate in this seminar and jointly discuss the development direction of future instruments.

　Wang Erkang, Academician of Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, brought a wonderful report entitled "A Brief discussion on Some New Achievements of modern analytical scientific instruments in China". In the report, Academician Wang Erkang briefly introduced some innovative achievements in the development of modern analytical science in China, and detailed his team's major research on the establishment of solid-state electrochemiluminescence immunoassay instruments based on the reconstruction of magnetic spheres at the interface. Academician Wang Erkang said that these scientific research achievements have promoted the industrialization and engineering of a series of instruments and equipment and the vigorous development of basic scientific research.

　Academician Dong Shaojun, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, presented a report entitled "Research and Development of the detection of key parameters of Environmental Water Quality". In his report, Academician Dong Shaojun innovatively proposed the detection method of in-situ culture microbial membrane, which was proved to have strong stability, good reproducibility and reliable detection results. Academician Dong Shaojun introduced the research progress of his research team in WTT method. It has overcome many disadvantages of using animals as subjects and realized the research strategy of in situ/on-line electrochemical method to detect total toxicity in water body. In view of the reality of environmental pollution by E. coli, the research team designed and synthesized a new type of E. coli specific indicator probe, and proposed a method of catalyzing hydrolysis of the enzyme substrate/promoting rapid dissociation of the fluorescent probe by nanase.

Academician Zhuang Songlin of the University of Shanghai for Science and Technology and Professor Zhu Yiming of the University of Shanghai for Science and Technology jointly brought a wonderful report entitled "Research on Terahertz Photonics Core Devices and their Systems". Academician Zhuang Songlin introduced the size and composition of his research team and the future development plan to the participants. Professor Zhu Yiming introduced the performance characteristics of core devices such as new terahertz radiation chips, highly sensitive detection technology, and ultra-large depth of field imaging devices. The present situation of terahertz spectrometer in our country is analyzed. At the same time, the application cases of the terahertz BOPP system developed by his team in kidney fiber detection, American ginseng detection from different places, terahertz public safety detection, semiconductor detection and other aspects are also introduced, as well as the detection effects of the chip terahertz ultra-sensitive detection system in crude oil traceability, biosensing, chiral enantiomeric detection and inspection. Finally, Professor Zhu Yiming said that the terahertz optical comb system is the key technical solution, and shared the research progress of Terahertz near-field superresolution microscopy with the participants.

Academician Yang Xiurong of Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, brought a wonderful report entitled "Innovation of scientific instruments is the Forerunner and booster of scientific and technological development". In the report, Academician Yang Xiurong first summarized the relevant research of X-ray derivative technology, nuclear magnetic resonance technology, cryo-electron microscopy technology, mass spectrometry technology, Raman spectroscopy, laser spectroscopy and other technologies that won the Nobel Prize in chemistry, emphasizing the importance of the development of scientific instruments. Academician Yang Xiurong said that advanced scientific instruments are not only the premise of knowledge innovation and technological innovation, but also one of the main contents of innovation research, and is an important manifestation of innovation achievements. Secondly, Academician Yang Xiurong, in combination with the analytical instruments developed by the national instrument development project undertaken by him, and the development history of scientific instruments of the State Key Laboratory of Electroanalytical Chemistry, introduced the achievements made in the development of electrochemical analytical instruments in China, the role played in promoting scientific development and the development status quo, and shared the development situation of electrochemical analytical instruments in China with the participants. The innovative features of EC-DPI instrument independently developed by his team were highlighted. At the end of the report, Academician Yang Xiurong analyzed the development trend of scientific instruments and stressed the important role of "new tools" in scientific innovation research.

Li Haiyang, researcher of Dalian Institute of Chemical Physics, Chinese Academy of Sciences, brought a wonderful report entitled "Research Progress of high-performance photoionization mass spectrometer". In the report, researcher Li Haiyang focused on three aspects: photoionization technology and photoionization source, high-performance photoionization mass spectrometer and industrialization, photoionization ion migration spectrometer and industrialization. The research progress of vacuum ultraviolet photoionization (VUV-PI) and ion analyzer used in mass spectrometry and ion migration spectrometry is reviewed. Researcher Li Haiyang proposed to carry out large-scale practical applications of the instrument in major national needs such as national security, life and health, and industrial processes, as well as in the fields of national economy and people's livelihood.

　Academician Jiang Guibin of the Research Center for Ecological and Environmental Sciences of the Chinese Academy of Sciences presented a video report entitled "Development of a New instrument System for Pollutant Screening and Risk Assessment". Academician Jiang Guibin first popularized the definition of new pollutants to the participants, and the report focused on three aspects: new pollutants and their background, the development of screening technology for new pollutants, and the development of group toxicology analyzer. In the report, Academician Jiang Guibin summarized the results of his and his team's investigation of environmental pollutants over the years, and analyzed the status quo of new pollutants detection in China. The design idea of the group toxicology analyzer was emphatically introduced, and the application performance of the group toxicology analyzer in complex media sample extraction, preparation and structure identification technology, and high throughput multi-target toxicity screening technology was shared. Finally, Academician Jiang Guibin said that new pollutants will accompany the whole process of human evolution, and its control can not be achieved overnight.

Sun Hongbo, Institute of Electrical Engineering, Chinese Academy of Sciences, gave a presentation entitled "Extreme field NMR and Interdisciplinary". In the report, Sun Hongbo mainly reported the latest research progress of extreme field NMR technology and many interdisciplinary disciplines. The basic principle and technical development of extreme field NMR are introduced, and its application in different disciplines is discussed. Sun Hongbo said that in future research, his team will further promote the development of extreme field NMR technology, broaden its application range in interdisciplinary disciplines, and make greater contributions to solving major scientific and social problems.

Professor Zhang Xinrong from Tsinghua University presented a research report entitled "Molecular Recognition and intelligent Recognition in Chemical Measurement". Professor Zhang Xinrong said that various kinds of precision analytical instruments have been used for the purpose of obtaining molecular information. In the report, Professor Zhang Xinrong popularized to the participants a number of molecular recognition and intelligent recognition related scientific research cases, such as olfactory bionics, face recognition for chemical measurement, AI looking at X-ray to identify race, and analysis methods established at the level of cluster motion by vision-based intelligent recognition technology. It is pointed out that the science of chemical measurement is at the key point of the third technological change after "the development of thermodynamics and dynamics theory accompanied by physics" and "the industrial revolution and the progress of machine building technology in the mid-19th century". Finally, Professor Zhang Xinrong said that molecular recognition and intelligent recognition are the directions that entrepreneurs should consider in the future.

　Professor Liu Huwei from Peking University presented an exciting report entitled "On-line Co-application of Surface Plasmon Resonance and mass Spectrometry". Prof. Liu Huwei said that surface plasmonic resonance (SPR) technology is widely used in the study of intermolecular interactions, and it can conduct marker-free, highly sensitive, real-time rapid analysis of biomolecular interactions. However, due to its lack of molecular structure identification capability, its application is limited when faced with interaction processes involving unknown substances. The combination of SPR method with analytical methods such as mass spectrometry (MS) with structural identification capability will make up for the shortcomings of SPR itself and greatly improve the analytical capability of SPR.

Professor Zepal Abudzi from Minzu University of China presented a wonderful report entitled "Progress in Open Mass Spectrometry Imaging Technology and Application". According to Prof. Zepal Albunzi, his research team independently developed a new atmospheric pressure open ionization technology and its labeling free, convenient and highly sensitive mass spectrometry molecular imaging technology and device (AFADESI-MSI), and combined this technology with metabolomics to develop spatially-resolved metabolomics technology and methods. It has promoted the research work in biomedicine and other fields. Professor Zaipal Abbotz highlighted his team's use of AFADESI-MSI technology and spatially resolved metabolomics methods, New techniques and methods of tissue in situ derivatization, highly sensitive and highly selective MSI analysis of low abundance and difficult ionizing metabolites, in vivo drug analysis, pharmacodynamic and toxic mechanism studies, tumor metabolic reprogramming mechanism, in situ screening of tumor metabolic markers and molecular pathological diagnosis, revealing tumor metabolic heterogeneity and diabetic spatial metabolic changes, diabetic nephropathy/encephalopathy Important progress has been made in the study of disease mechanism.

　Professor Lin Jinming from Tsinghua University gave a presentation entitled "Analysis of drug metabolism in Cells with microfluidic chip mass spectrometry". In the report, Professor Lin Jinming mainly introduced that his research team has carried out long-term research on the development and application of microfluidic chip and mass spectrometry co-instrument, successfully developed a microfluidic chip mass spectrometry co-analytical device, and implemented the industrialization of technology transfer enterprises. Professor Lin Jinming said that the microfluidic chip's micron scale space and cell size can be well matched, and it can easily simulate and precisely control the microenvironment of cell growth, which is an ideal platform for studying cell interactions, signal transduction and communication, and cell drug metabolism and delivery.

　Zhang Feng, a researcher from the Chinese Academy of Inspection and Quarantine Science, brought a wonderful report entitled "Accurate Confirmation and rapid early warning". Researcher Zhang Feng introduced the development history of mass spectrometry technology to the participants, and said that accurate confirmation and rapid warning are the development trend and goal of mass spectrometry technology. Zhang Feng mainly introduced the research progress of lipidomics using ion mobility technology and the research results of harmful metabolism using mass spectrometry technology. At the end of the report, researcher Zhang Feng said that mass spectrometers should continue to innovate to provide a strong and powerful guarantee for the analysis and testing industry.

Deng Yuqiang, a researcher from the Chinese Academy of Metrology, brought a wonderful report entitled "Establishment of Terahertz radiation Power Measurement Standards", introducing his research team's research in terahertz measurement technology. According to Deng Yuqiang, the research team has made progress in terahertz power measurement, terahertz spectrum measurement, terahertz frequency measurement and terahertz radiation spatial distribution measurement. A terahertz absorbent material with wide absorption bandwidth and high absorptivity and a terahertz radiation power meter are developed. The terahertz power value is reproduced by means of electric power substitution, which is in good agreement with the laser radiation power standard.

The report presented by Professor Ye Xia from Jiangsu Institute of Technology is entitled "Research Application and Frontier Progress of intelligent rehabilitation instrument (robot) in stroke rehabilitation". Professor Ye Xia first introduced the research background and significance of intelligent rehabilitation robot. Professor Ye Xia said that rehabilitation robots are an important means to promote stroke rehabilitation. Secondly, Professor Ye Xia showed the participants the progress of the application of rehabilitation robots in rehabilitation training. The Flexbot-U system is taken as an example to demonstrate the clinical effect of rehabilitation robot in assisting patients to recover. Professor Ye Xia believes that human-computer interaction is very important in rehabilitation robot-assisted patient rehabilitation treatment. The existing problems and future development trend of rehabilitation robot are analyzed. Finally, Professor Ye Xia focused on the performance characteristics of the lower limb rehabilitation robot, upper limb rehabilitation robot, multi-modal interactive intelligent wheelchair, disabled elderly rehabilitation and nursing system developed by his team in terms of structural design and control system, and the research progress of the cavity mirror detection software system currently under development.

　Professor Duan Yixiang from Sichuan University presented a wonderful report entitled "Development and Application of high-resolution fast response mass spectrometry Technology and Instruments". In his presentation, Professor Duan Yixiang focused on the application of mass spectrometers in cancer screening. According to Professor Duan Yixiang, his research team took the lead in the development of mass spectrometer system for human exhaled lung cancer early screening mass spectrometry system, and conducted clinical application research. The instrument has the advantages of ultra-low cost, high accessibility and high accuracy. Professor Duan Yixiang also introduced the detection effect of real-time mass spectrometry exhaled gas detection in COVID-19 detection and the application of real-time mass spectrometer in VOCs navigation monitoring.

Professor Duan Yixiang from Sichuan University presented a wonderful report entitled "Development and Application of high-resolution fast response mass spectrometry Technology and Instruments". In his presentation, Professor Duan Yixiang focused on the application of mass spectrometers in cancer screening. According to Professor Duan Yixiang, his research team took the lead in the development of mass spectrometer system for human exhaled lung cancer early screening mass spectrometry system, and conducted clinical application research. The instrument has the advantages of ultra-low cost, high accessibility and high accuracy. Professor Duan Yixiang also introduced the detection effect of real-time mass spectrometry exhaled gas detection in COVID-19 detection and the application of real-time mass spectrometer in VOCs navigation monitoring.

　Professor Xu Guangtong of the Research Institute of Petrochemical Science brought a wonderful report entitled "Proton exchange Membrane Fuel cell vehicle Hydrogen detection and standard system research and application Demonstration". Professor Xu Guangtong said in the report that the development of the hydrogen energy industry has entered the fast lane, through nearly 4 years of research and practice, has established a relatively complete hydrogen energy detection method system and technical system, can provide a complete set of testing solutions for laboratory, online and mobile scenarios. At the same time, the hydrogen test series of group standards have been developed, and the development of national standards is in progress, laying the foundation for the next step of product standard revision. Professor Xu Guangtong introduced that the first hydrogen testing laboratory certified by CMA and CNAS in China has been established, supporting the development of the hydrogen energy industry chain and the construction of hydrogen energy demonstration cities, and providing a guarantee for the hydrogen quality of the Beijing Winter Olympics. Finally, Professor Xu Guangtong said that there is still a lot of room for development of hydrogen detection technology and domestic test instruments suitable for multiple scenarios.

　Yin Wei, a researcher from Beijing Research Institute of Chemical Engineering, brought a wonderful report entitled "Development and Prospect of Environmental Monitoring and analysis Technology in China". Prof. Yin Wei shared with the participants the current standard system status of environmental monitoring in China. Yin Wei, a researcher, said that the development of environmental monitoring technology is an important support for green mountains. The current environmental monitoring task, relying on the research results in the field of instrument manufacturing, is developing towards the direction of integration of heaven and earth, digitalization, automation, and networking, and has become a strong pillar of environmental protection.

Chinese Academy of Agricultural Sciences researcher Cheng Jie brought the title of the report "edible agricultural products quality safety and efficient identification and accurate detection technology and equipment." Researcher Cheng Jie introduced two key research directions, namely feed toxicology and feed safety analysis basis. And reported the progress of its work to the participants, one is to build a clenbuterol supervision tool to ensure food safety and life and health; The second is to overcome the problem of insufficient sample pretreatment flux; The third is to break through the bottleneck of insufficient accuracy of rapid measurement technology and improve the recognition of rapid measurement results; The fourth is to break the research blind spot of the migration and transformation of POPs from environment to food. The research results of these four works have been highly recognized by experts and scholars at home and abroad.

At this point, the 21st seminar on Advanced Technology of Modern Scientific Instruments is completed. At the same time, the conference held the terahertz spectrometer and related technologies branch, the modern instrument analysis application branch, the food and agricultural product quality and safety monitoring technology and equipment branch.

In addition to the wonderful reports of many academicians, experts and scholars, the excellent exhibitors in the industry also actively participated in it, and I would like to express my heartfelt thanks to them: Beijing Haiguang Instrument Co., LTD., Beijing Jingpin Si Si Technology Co., LTD., Chengdu Kerui Technology Co., LTD., Bo Terahertz Information Technology (Wuhan) Co., LTD., Daheng New Era Technology Co., LTD., Beijing Shenmu Technology Co., LTD., Huirui Photoelectric Technology (Beijing) Co., LTD., Suzhou Core Array Electronics Co., LTD., Qingdao Qingyuan Fengda Terahertz Technology Co., LTD., Sichuan See Weizhizhi Technology Co., LTD., Shanghai Zhuoguang Instrument Technology Co., LTD., Shanghai Henghe Scientific Instrument Co., LTD., Beijing Greideman Instrument Equipment Co., LTD., Rumecos Analytical Instrument Co., LTD., Sichuan Shuke Instrument Co., LTD., Beijing Haotianhui Instrument Co., LTD., Beijing Hexin Tongtong Technology Development Co., LTD., Nanjing Shuangxue Analytical Instrument Co., LTD., Beijing Juxin Chifeng Science and Technology Co., LTD Technology Co., LTD., Huapu (Beijing) Technology Co., LTD., Beijing Tongzhou Weipu Technology Co., LTD., Beijing East-West Analytical Instruments Co., LTD.